منابع مشابه
Streptomycin resistant gonorrhoea.
The readiness with which many organisms develop resistance to streptomycin is well recognized; Willcox (1953) ventured to predict that "should streptomycin be widely used for gonorrhoea it is possible that its efficiency may decline". At the Liverpool Royal Infirmary during the past 4 years routine treatment of male patients suffering from gonorrhoea has been by a single injection of streptomyc...
متن کاملTreatment of gonorrhoea with streptomycin.
Although a number of papers on the treatment of gonorrhoea with streptomycin have been published during the last four years, few reports have come from Great Britain. Chinn and others (1947) obtained seventy cures out of 72 patients who were given 0-2 to 0-5 g. streptomycin, and Pulaski (1947) reported success in nine cases. Willcox (1948), employing a single injection of 0-2 to 0-6 g. had succ...
متن کاملStreptomycin-resistant gonorrhoea in the female.
There were 17,845 infections of gonorrhoea reported in 1955 by the V.D. clinics of England and Wales. How many other cases were treated and not reported is unknown. Several reasons have been advanced to explain why gonorrhoea should still be so prevalent after 10 years of penicillin therapy in spite of the known effectiveness of this antibiotic. The chief reason is surely the difficulty of erad...
متن کاملRelapse of gonorrhoea after treatment with penicillin or streptomycin.
The earliest workers with penicillin observed that it was extremely effective in vitro against the gonococcus. Florey and his co-workers (Abraham, Chain, Fletcher, Gardner, Heatley, Jennings, and Florey, 1941) found the gonococcus to be the most sensitive of a wide variety of pathogens they tested against penicillin. Clinical experience supported laboratory findings, and penicillin became, and ...
متن کاملStreptomycin resistance in a streptomycin-producing microorganism.
Cell-free extracts of Streptomyces bikiniensis contain an adenosine 5'-triphosphate-dependent kinase which inactivates streptomycin (Sm) and dihydrostreptomycin by phosphorylation. The products have been identified as streptomycin 6-phosphate and dihydrostreptomycin 6-phosphate. Activity was not present in logarithmic-phase cells, which were susceptible to 25 mug of Sm per ml. In stationary-pha...
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ژورنال
عنوان ژورنال: BMJ
سال: 1948
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.4588.1015